3D structures from the PDB for "Aldo-keto reductase family 1 member B1" AND "BDBM16313"
(Proteins have >= 85% sequence identity and ligands are exact matches)

Seq IdentityJmol DisplayPDB Title
2R24100%JmolHUMAN ALDOSE REDUCTASE STRUCTURE
2PEV>99%JmolCOMPLEX OF ALDOSE REDUCTASE WITH NADP+ AND SIMALTANEOUSLY BOUND COMPETETIVE INHIBITORS FIDARESTAT AND IDD594. CONCENTRATION OF FIDARESTAT IN SOAKING SOLUTION EXCEEDS CONCENTRATION OF IDD594.
2I17>99%JmolHUMAN ALDOSE REDUCTASE IN COMPLEX WITH NADP+ AND THE INHIBITOR IDD594 AT TEMPERATURE OF 60K
2I16>99%JmolHUMAN ALDOSE REDUCTASE IN COMPLEX WITH NADP+ AND THE INHIBITOR IDD594 AT TEMPERATURE OF 15K
3GHS>99%JmolHUMAN ALDOSE REDUCTASE IN COMPLEX WITH NADP+ AND THE INHIBITOR IDD594. INVESTIGATION OF GLOBAL EFFECTS OF RADIATION DAMAGE ON PROTEIN STRUCTURE. SECOND STAGE OF RADIATION DAMAGE.
3GHT>99%JmolHUMAN ALDOSE REDUCTASE IN COMPLEX WITH NADP+ AND THE INHIBITOR IDD594. INVESTIGATION OF GLOBAL EFFECTS OF RADIATION DAMAGE ON PROTEIN STRUCTURE. THIRD STAGE OF RADIATION DAMAGE.
1US0>99%JmolHUMAN ALDOSE REDUCTASE IN COMPLEX WITH NADP+ AND THE INHIBITOR IDD594 AT 0.66 ANGSTROM
2PF8>99%JmolCOMPLEX OF ALDOSE REDUCTASE WITH NADP+ AND SIMALTANEOUSLY BOUND COMPETETIVE INHIBITORS FIDARESTAT AND IDD594. CONCENTRATION OF FIDARESTAT IN SOAKING SOLUTION IS EQUAL TO CONCENTRATION OF IDD594.
2PFH>99%JmolCOMPLEX OF ALDOSE REDUCTASE WITH NADP+ AND SIMALTANEOUSLY BOUND COMPETETIVE INHIBITORS FIDARESTAT AND IDD594. CONCENTRATION OF FIDARESTAT IN SOAKING SOLUTION IS LESS THAN CONCENTRATION OF IDD594.
2QXW>99%JmolPERDEUTERATED ALR2 IN COMPLEX WITH IDD594
3GHR>99%JmolHUMAN ALDOSE REDUCTASE IN COMPLEX WITH NADP+ AND THE INHIBITOR IDD594. INVESTIGATION OF GLOBAL EFFECTS OF RADIATION DAMAGE ON PROTEIN STRUCTURE. FIRST STAGE OF RADIATION DAMAGE
3LD5>99%JmolHUMAN ALDOSE REDUCTASE MUTANT T113S COMPLEXED WITH IDD594
3LBO>99%JmolHUMAN ALDOSE REDUCTASE MUTANT T113C COMPLEXED WITH IDD594
3LZ5>99%JmolHUMAN ALDOSE REDUCTASE MUTANT T113V COMPLEXED WITH IDD594
3LQL>99%JmolHUMAN ALDOSE REDUCTASE MUTANT T113A COMPLEXED WITH IDD 594
3ONB>99%JmolBOND BREAKAGE AND RELOCATION OF A COVALENTLY BOUND BROMINE OF IDD594 IN A COMPLEX WITH HAR T113A MUTANT AFTER EXTENSIVE RADIATION DOSE
3ONC>99%JmolBOND BREAKAGE AND RELOCATION OF A COVALENTLY BOUND BROMINE OF IDD594 IN A COMPLEX WITH HAR T113A MUTANT AFTER MODERATE RADIATION DOSE